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DSM Reference HomeDSM-IV and DSM-IV-TR:Major Depressive Disorder, Single EpisodeFor and individual to be diagnosed with this Depressive Disorder they must have experienced at least one Major Depressive Episode, but no Manic, Hypomanic, or Mixed Episodes. Diagnostic criteria for 296.2x Major Depressive Disorder, Single Episode(Warning!) A. Presence of a single Major Depressive Episode. B. The Major Depressive Episode is not better accounted for by Schizoaffective Disorder and is not superimposed on Schizophrenia, Schizophreniform Disorder, Delusional Disorder, or Psychotic Disorder Not Otherwise Specified. C. There has never been a Manic Episode, a Mixed Episode, or a Hypomanic Episode. Note: This exclusion does not apply if all of the manic-like, mixed-like, or hypomanic-like episodes are substance or treatment induced or are due to the direct physiological effects of a general medical condition. Specify (for current or most recent episode):
Based on the Diagnostic & Statistical Manual of Mental Disorders, 4th edition APA The online Diagnostic & Statistical Manual of Mental Disorders lists most of the major psychological disorders and illnesses and lists the criteria that must be fulfilled in order for a diagnosis to be made. This resource is not a substitute for proper professional psychiatric diagnosis.
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Last Updated
07 January 2026
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